Corneal Neurotization vs. Cenergermin for Neurotrophic Keratitis: A Pilot Study

NANot yet recruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

August 1, 2026

Study Completion Date

August 1, 2027

Conditions
Neurotrophic Keratitis
Interventions
PROCEDURE

Corneal Neurotization

Surgical technique involving the transfer of healthy donor sensory nerves to the anesthetic cornea to restore corneal innervation and sensation in patients with neurotrophic keratitis.

DRUG

Cenergermin

Topical recombinant human nerve growth factor (rhNGF) approved for the treatment of neurotrophic keratitis. Administered as eye drops, it promotes epithelial healing and nerve regeneration.

Trial Locations (1)

N6A 4V2

Ivey Eye Institute, St. Joseph's Health Care London, London

All Listed Sponsors
lead

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

OTHER

NCT07073729 - Corneal Neurotization vs. Cenergermin for Neurotrophic Keratitis: A Pilot Study | Biotech Hunter | Biotech Hunter