NCT07072923View on ClinicalTrials.gov

Antibiotic Impregnated Beads in Osteomyelitis

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

September 30, 2027

Conditions
Osteomyelitis of the FootAntibiotic Impregnated BeadsOsteomyelitis of Lower Extremities
Interventions
DRUG

Antibiotic loaded calcium sulfate beads

Calcium sulfate beads will be loaded with best available antibiotics based on surgeon/infectious disease specialist determination from the following options (vancomycin, daptomycin, cefazolin, cefepime, tobramycin, amphotericin B, micafungin, and voriconazole).

DEVICE

Calcium sulfate beads (sham beads)

Calcium sulfate beads will be prepared without added antibiotics and placed during the second surgery.

All Listed Sponsors
lead

University of Arizona

OTHER