A Clinical Study of Ultrasound-guided Botulinum Toxin A Into Salivary Gland for Sialorrhea After True Bulbar Palsy

NAEnrolling by invitationINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

June 1, 2024

Primary Completion Date

August 1, 2025

Study Completion Date

September 1, 2025

Conditions
Sialorrhea True Bulbar Palsy Medullary Injury
Interventions
DRUG

Ultrasound-Guided Botulinum Toxin Type A (BoNT-A) Salivary Gland Injection

"Ultrasound-guided injection of BoNT-A (specific dosage, e.g., 100 units) into target salivary glands ( parotid and submandibular glands) at baseline."

DRUG

Control (Normal saline)

"Intervention: Participants receive routine swallowing rehabilitation training only.~Details of training: The training includes standard techniques to improve swallowing function, such as oral motor training, empty swallowing exercises, and ice stimulation. The frequency and duration of training are consistent across all participants in this arm to ensure standardization."

Trial Locations (1)

Unknown

Fuxing Hospital Affiliated to Capital Medical University, Beijing

All Listed Sponsors
lead

houyajing

OTHER