Efficacy and Safety Analysis of Polylauric Alcohol More Stable Foam Versus Ordinary Foam in the Treatment of Head and Neck Venous Malformations

NARecruitingINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

December 30, 2025

Study Completion Date

June 30, 2026

Conditions
Venous Malformation
Interventions
COMBINATION_PRODUCT

The addition of sodium hyaluronate to poly (cinnamyl alcohol-RRB- produces a more stable foam

According to the study, the half-life of 1% poly (cinnamyl alcohol-RPol(POL) foam with a liquid-to-gas ratio of 1:4 was 142.8(64.32) seconds, in this study, the half-life of the foam made from 1% POL containing 0.05% hyaluronic acid (HA) was 390.4(613.06) seconds, human blood contains a certain amount of HA, according to the literature reported that 0.05% concentration of HA injected into human blood is safe, so this more stable foam preparation method was patented, and published in international journals.

Trial Locations (1)

250000

RECRUITING

Shandong University Qilu Hospital, Jinan

All Listed Sponsors
lead

Qilu Hospital of Shandong University

OTHER