Simultaneous Bilateral Radiofrequency Thalamotomy for Medication-Refractory Essential Tremor

NARecruitingINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

July 3, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

December 31, 2026

Conditions
Essential Tremor
Interventions
PROCEDURE

Simultaneous Bilateral RF Thalamotomy

This intervention involves simultaneous bilateral radiofrequency (RF) lesioning of the ventral intermediate nucleus (Vim) of the thalamus using a stereotactic frame under local anesthesia. The procedure begins with RF ablation on the side contralateral to the dominant hand. Intraoperative MRI is then performed to confirm the absence of hemorrhagic complications. If no bleeding or other adverse events are detected, the procedure proceeds to the contralateral Vim. If hemorrhage is identified, the surgery is terminated after unilateral treatment. This technique allows for immediate bilateral tremor reduction in patients with medication-refractory essential tremor, while prioritizing patient safety through intraoperative imaging-based decision-making.

Trial Locations (1)

1628666

RECRUITING

Tokyo Women's Medical University, Department of Neurosurgery, Shinjuku-Ku

All Listed Sponsors
lead

Tokyo Women's Medical University

OTHER

NCT07066358 - Simultaneous Bilateral Radiofrequency Thalamotomy for Medication-Refractory Essential Tremor | Biotech Hunter | Biotech Hunter