5
Participants
Start Date
July 3, 2025
Primary Completion Date
October 31, 2026
Study Completion Date
December 31, 2026
Simultaneous Bilateral RF Thalamotomy
This intervention involves simultaneous bilateral radiofrequency (RF) lesioning of the ventral intermediate nucleus (Vim) of the thalamus using a stereotactic frame under local anesthesia. The procedure begins with RF ablation on the side contralateral to the dominant hand. Intraoperative MRI is then performed to confirm the absence of hemorrhagic complications. If no bleeding or other adverse events are detected, the procedure proceeds to the contralateral Vim. If hemorrhage is identified, the surgery is terminated after unilateral treatment. This technique allows for immediate bilateral tremor reduction in patients with medication-refractory essential tremor, while prioritizing patient safety through intraoperative imaging-based decision-making.
RECRUITING
Tokyo Women's Medical University, Department of Neurosurgery, Shinjuku-Ku
Tokyo Women's Medical University
OTHER