Sex Hormones as Regulators of the Age- and Sex-dependent Benefits of Caloric Restriction

NARecruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

July 9, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
Overweight and Obese AdultsHealthy
Interventions
OTHER

Phase 1 - Maintenance Diet

3d maintenance diet (MT, fixed macronutrient composition of 15% protein, 30% fat and 55% CHO), fed to energy requirements (1.3 X RMR)

OTHER

Phase 2 - Weight loss diet

6 week calorie restricted high protein diet (CR, fixed macronutrient composition as 30% protein, 35% fat and 35% CHO) fed to energy requirements \[0.8 X Resting Metabolic Rate (RMR)\], with stepwise reduction of 100kcal/d at week 3 and 5

Trial Locations (1)

Unknown

RECRUITING

Rowett Institute, University of Aberdeen, Aberdeen

All Listed Sponsors
collaborator

University of Edinburgh

OTHER

lead

University of Aberdeen

OTHER

NCT07065643 - Sex Hormones as Regulators of the Age- and Sex-dependent Benefits of Caloric Restriction | Biotech Hunter | Biotech Hunter