ERCP Versus PTBD for Severe Acute Cholangitis Caused by Bile Duct Stones

NACompletedINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

May 1, 2021

Primary Completion Date

May 31, 2024

Study Completion Date

May 31, 2024

Conditions
Severe Acute Cholangitis
Interventions
PROCEDURE

Endoscopic Retrograde Cholangiopancreatography

Performed under intravenous anesthesia. A duodenoscope was advanced to the major duodenal papilla. After cannulation and cholangiography, purulent bile was aspirated. Biliary sphincterotomy was performed in most patients (95.2%), followed by stone extraction using a balloon catheter or basket. A 7-10 Fr nasobiliary tube was placed for drainage in all patients. Prophylactic rectal indomethacin (100mg) was also administered.

PROCEDURE

Percutaneous Transhepatic Biliary Drainage

Performed under general anesthesia with endotracheal intubation and ultrasound guidance. An 18G needle was used to puncture a dilated intrahepatic bile duct. After guidewire placement, an 8-10 Fr drainage catheter was inserted for either internal-external drainage (if the guidewire could pass into the duodenum) or purely external biliary drainage.

Trial Locations (1)

430030

Wuhan No.1 Hospital (Wuhan Hospital of Traditional Chinese & Western Medicine), Wuhan

All Listed Sponsors
lead

Wuhan Integrated Traditional Chinese and Western Medicine Hospital

OTHER