Adding Dexmedetomidine to Mannitol to Attenuate the Increase of Intracranial Pressure

PHASE2/PHASE3RecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

April 12, 2024

Primary Completion Date

December 15, 2025

Study Completion Date

January 1, 2026

Conditions

Dexmedetomidine

Interventions

DRUG

Dexmedetomidine with Mannitol

receive 1 mcg/kg of dexmedetomidine added to 0.4 mcg/kg of mannitol

DRUG

Mannitol (20%)

receive 0.5 g/kg of mannitol

Trial Locations (1)

RECRUITING

facility of medicine Cairo university, Cairo

All Listed Sponsors

lead

Cairo University

OTHER