56
Participants
Start Date
January 1, 2021
Primary Completion Date
April 1, 2021
Study Completion Date
April 1, 2021
Nicotinamide(NAM)(10%)
The active niacinamide form of vitamin B3, NAM is routinely employed as a pigmentation-reducing agent in melasma treatment protocols
Supramolecular salicylic acid(SSA) (30%)
Salicylic acid, a superficial chemical peel, has been widely used in treating melasma. Breakthroughs in supramolecular design have addressed its irritancy profile through engineered SA complexes with improved water dispersibility
Supramolecular salicylic acid simulator
the same course of treatment in the same dosage form that does not contain salicylic acid
Nicotinamide simulator
the same course of treatment in the same dosage form that does not contain nicotinamide
The Second Affiliated Hospital of Xi'an Jiaotong Universi, Xi'an
Second Affiliated Hospital of Xi'an Jiaotong University
OTHER