186
Participants
Start Date
July 31, 2025
Primary Completion Date
January 31, 2027
Study Completion Date
January 31, 2027
Deep cervical lymphatic-venous anastomosis
Lymph node reconstruction was carried out using microsurgical techniques,improve cerebral lymphatic circulation and return, accelerate the excretion of pathological proteins, the metabolic products of the brain, from the brain. This is to delay the degenerative changes of the brain and the progression of Alzheimer's disease.
Donepezil drug treatment
All patients stopped taking cognitive-enhancing drugs after enrollment, and marketed therapeutic drugs include ginkgo biloba, high-dose vitamin E, lecithin, estrogen, non-steroidal anti-inflammatory drugs, memegan, etc.
Shanghai Jiao Tong University School of Medicine
OTHER