DENTOFACIAL-PBT Stage 2 - Feasibility Study

Not yet recruitingOBSERVATIONAL
Enrollment

255

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

September 30, 2026

Study Completion Date

January 31, 2027

Conditions
Head and Neck CancerRadiotherapy Side EffectAdverse Effect of Radiation TherapyChildhood CancerDental Developmental Disorders and AnomaliesFacial DeformityJaw; Developmental DisorderRadiation Toxicity
Interventions
RADIATION

Orthopantomogram (or a set of Lateral Oblique Radiographs)

A dental assessment will be conducted on eligible participants who still attend annual review appointments in the Oncology Departments at the Royal Manchester Children's Hospital or at The Christie NHS Foundation Trust (approximately 10% of eligible study population). The dental assessment will include the following: a tooth chart, a basic periodontal examination (BPE), a brief orthodontic assessment (incisor, molar and skeletal classification including any asymmetry), caries assessment and an assessment of any dental development disturbances. Clinical photographs of the teeth and face will be taken with a patient's consent. If clinically justified, an OPT will be taken. If cooperation for an OPT proves challenging, lateral obliques as an alternative radiographic image modality will be considered.

Trial Locations (2)

M13 9WL

Manchester University NHS Foundation Trust, Manchester

M20 4BX

The Christie NHS Foundation Trust, Manchester

All Listed Sponsors
collaborator

The Christie NHS Foundation Trust

OTHER

lead

Manchester University NHS Foundation Trust

OTHER_GOV