Constraint-induced Movement Therapy Versus Task-oriented Training On Upper Extremity Function Post-Botox Injection in Stroke Patients

NANot yet recruitingINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

June 30, 2025

Primary Completion Date

October 1, 2025

Study Completion Date

November 1, 2025

Conditions
Constraint Induced Movement TherapyTask Oriented TrainingBotox InjectionUpper Extremity FunctionStroke
Interventions
OTHER

The designed physiotherapy program

"* Scapular and thoracic mobilization, active assisted and passive exercises, and positioning such as weight bearing on the affected upper limb.~* Strengthening of the shoulder flexors and elbow and wrist extensors.~* Stretching exercises of the spastic muscles (shoulder extensors, elbow and wrist flexors.)"

DRUG

The Botulinum toxin injection

The injection of 1000 units per upper extremity will be done into the biceps brachii muscle at 2 sites, and 150 units into the flexor carpi radialis muscle at 1 site per muscle, using anatomical landmarks similar to routine electromyography.

OTHER

Task oriented training

The training involves 30 minutes of bilateral functional tasks like carrying a block, grabbing and folding a towel, staking cups upright, holding a glass and drinking water, throwing a ball into a basket, and moving pegs.

OTHER

Constrained induced movement therapy

The therapy session focuses on enhancing the affected arm's functional tasks, such as throwing a ball, holding a glass, combing hair, turning on and off a light switch, grasping and releasing blocks, pouring from glass to another, moving cups, and moving pegs. Participants are instructed to wear a restrictive mitt on their non-paretic hand for 6 hours a day for 4 days, 7 weeks, and 12 weeks, with the mitt removed for safety, hygiene, or agreed-on activities.

Trial Locations (1)

Unknown

outpatient clinics of Mansoura university hospital, Al Mansurah

All Listed Sponsors
lead

Cairo University

OTHER

NCT07057050 - Constraint-induced Movement Therapy Versus Task-oriented Training On Upper Extremity Function Post-Botox Injection in Stroke Patients | Biotech Hunter | Biotech Hunter