Early Versus Late Stopping of Antibiotics in Adults With High-risk Hematological Malignancies/Receiving Cellular Therapies and Fever

NANot yet recruitingINTERVENTIONAL
Enrollment

214

Participants

Timeline

Start Date

July 5, 2025

Primary Completion Date

July 5, 2027

Study Completion Date

September 5, 2027

Conditions
LeukemiaCART TherapyTransplantation, Stem CellInfections, Bacterial
Interventions
DRUG

Early antibiotic cessation alert

For all patients, antibiotics will be commenced at onset of fever. For those in the intervention arm an alert will fire in the electronic medical record once a patient is afebrile for 48-96 hours and clinically stable.

Trial Locations (2)

3000

Peter MacCallum Cancer Centre, Melbourne

3050

Royal Melbourne Hospital, Melbourne

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Melbourne Health

OTHER

lead

Peter MacCallum Cancer Centre, Australia

OTHER

NCT07051525 - Early Versus Late Stopping of Antibiotics in Adults With High-risk Hematological Malignancies/Receiving Cellular Therapies and Fever | Biotech Hunter | Biotech Hunter