NCT07051239View on ClinicalTrials.gov

Sleep Stimulation to Enhance Waste Clearance in the Brain

NANot yet recruitingINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

September 30, 2028

Study Completion Date

September 30, 2028

Conditions
HealthySubjective Cognitive Decline (SCD)Mild Cognitive Impairment (MCI)Alzheimer Disease (AD)
Interventions
OTHER

Closed-loop acoustic stimulation

At-home sleep will be monitored using an EEG headband. Non-awakening auditory stimuli will be delivered during non-rapid eye movement sleep (NREM), timed to the ascending phase of slow waves, using either active or control (sham) conditions.

Trial Locations (1)

Unknown

Hôpital Universitaire de Bruxelles, Brussels

All Listed Sponsors
collaborator

University of Amsterdam

OTHER

lead

Erasme University Hospital

OTHER

NCT07051239 - Sleep Stimulation to Enhance Waste Clearance in the Brain | Biotech Hunter | Biotech Hunter