80
Participants
Start Date
June 1, 2024
Primary Completion Date
December 20, 2024
Study Completion Date
January 25, 2025
Goal-Directed Fluid Therapy (GDFT)
This arm administers fluid and vasopressor therapy based on SVV (less than 15%) and CI (\>2.6 L/min/m²) targets using the Pressure Recording Analytical Method (PRAM) system with the help of intra-arterial pressure monitoring method. Basal fluid replacement is provided with 5 mL/kg/hr of Lactated Ringer's solution.
Conventional Fluid Therapy
This arm administers fluid and vasopressor therapy based on targets of Mean Arterial Pressure (MAP) 65-95 mmHg and hourly urine output minimum of 0.5 mL/kg/hr. Basal fluid replacement is provided with 5 mL/kg/hr of Lactated Ringer's solution.
Cukurova University, Adana
Cukurova University
OTHER