Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease

NARecruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

June 24, 2025

Primary Completion Date

June 24, 2027

Study Completion Date

June 24, 2028

Conditions
Charcot-Marie-Tooth Disease Type 1A
Interventions
OTHER

Quantitative neuromuscular MRI

Quantification of biomarkers as fat fraction, magnetization Transfer Ratio, muscular volume, relaxation time T2

OTHER

Skin biopsy

Performed on the arm or index finger, depending on patient age

OTHER

Clinical scores

ONLS, CMTES-R, CMT-Peds, CMT-FOM

OTHER

Blood test

10 ml sample

OTHER

Patient Report Outcomes Measures

pCMT-QoL, EVA, WALK-12, PGI-c, SF-12

Trial Locations (1)

13005

RECRUITING

Assistance Publique - Hôpitaux de Marseille, Marseille

All Listed Sponsors
collaborator

Association Française contre les Myopathies (AFM), Paris

OTHER

collaborator

University Medical Center Göttingen

UNKNOWN

lead

Assistance Publique Hopitaux De Marseille

OTHER

NCT07049588 - Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease | Biotech Hunter | Biotech Hunter