Efficacy and Safety of Contrast EUS-Guided Tissue Glue/Coil Devascularization vs. BRTO for Preventing Recurrent Gastric Variceal Bleeding

NANot yet recruitingINTERVENTIONAL
Enrollment

242

Participants

Timeline

Start Date

July 30, 2025

Primary Completion Date

January 31, 2028

Study Completion Date

June 30, 2028

Conditions
Gastric Varices Bleeding
Interventions
PROCEDURE

EUS-guided tissue glue/coil injection

Under linear array endoscopic ultrasound (EUS), puncture GVs with a 19G/22G needle, deploy coils, and inject 1-2ml tissue glue until blood flow in GVs disappears (or inject glue directly if coils are unsuitable). Treat moderate-to-severe esophageal varices (EVs) with band ligation during or after the procedure.

PROCEDURE

BRTO

Establish vascular access via the femoral or internal jugular vein, occlude gastrorenal shunts with a balloon catheter, and inject sclerosant foam. Treat moderate-to-severe EVs with band ligation within 5 days post-procedure.

Trial Locations (1)

610041

37 Guoxue Lane, Chengdu

All Listed Sponsors
lead

West China Hospital

OTHER

NCT07049146 - Efficacy and Safety of Contrast EUS-Guided Tissue Glue/Coil Devascularization vs. BRTO for Preventing Recurrent Gastric Variceal Bleeding | Biotech Hunter | Biotech Hunter