Sarcoma Surgery Wound Complications Comparing Usual Versus Negative Pressure Dressing

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

94

Participants

Timeline

Start Date

December 1, 2025

Primary Completion Date

February 28, 2027

Study Completion Date

September 30, 2027

Conditions
SarcomaNegative Pressure TherapyWound Complication
Interventions
DEVICE

Negative Pressure Wound Therapy (NPWT) Dressings

During wound closure, skin glue is not permitted as this interferes with the NPWT suction mechanism. The NPWT is a mesh-based dressing that will be applied following the transparent occlusive dressing as per the manufacturer's instructions. Patients assigned to NPWT will have their dressing connected to a suction device (ActiV.A.C.®, KCI) providing a constant negative pressure of 125mmHg and left in situ for between 5 and 7 days. The dressings and suction device are all CE-marked medical devices that are being used within their intended usage.

DEVICE

Standard Absorbent Dressings

The wound will be closed as per the standard surgical technique and the operating surgeon's preference. Following wound closure of sarcoma tumour resection, standard absorbent dressing will be applied as per local protocols and the pre-op plan

Trial Locations (1)

G4 0SF

Glasgow Royal Infirmary, Glasgow

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

University of Glasgow

OTHER

collaborator

Solventum

INDUSTRY

collaborator

Sarcoma UK

UNKNOWN

collaborator

CRUK Trials unit Glasgow

UNKNOWN

lead

NHS Greater Glasgow and Clyde

OTHER