Multi-omics Detection Techniques for Differentiating Benign and Malignant Pulmonary Nodules

RecruitingOBSERVATIONAL
Enrollment

150

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Lung Cancer (Diagnosis)Pulmonary Nodule Persistent
Interventions
BIOLOGICAL

PBMCS were isolated from the peripheral blood of hospitalized patients with pulmonary nodules and incubated with nanoparticles loaded with tumor antigens for a specific period of time to detect cancer

Research on the in vitro Stimulation of Pbmc by Tumor Antigen Nanoparticles PBMCS were isolated from the peripheral blood of hospitalized patients with pulmonary nodules and incubated with nanoparticles loaded with tumor antigens for a specific period of time to detect cancer-related T cells or cytokines in vitro. The content of this type of T cells or cytokines is positively correlated with tumors. On the contrary, the content of T cells or cytokines in patients with benign pulmonary nodules is negatively correlated with the tumor. Furthermore, the benign and malignant nature of pulmonary nodules in patients is determined through the combination of patient imaging data and clinicopathological data.

Trial Locations (1)

215000

RECRUITING

Soochow university, Suzhou

All Listed Sponsors
lead

Zhao Jun

OTHER