EEG-Triggered rTMS and Group Therapy for Adolescents With Depression and Self-Harm

NACompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

June 1, 2024

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Depression
Interventions
DEVICE

Real-time EEG-triggered Repetitive Transcranial Magnetic Stimulation (rTMS)

Stimulation target: left dorsolateral prefrontal cortex (DLPFC; F3 electrode position, 10-20 EEG system); Frequency: 10 Hz; Intensity: 110% of resting motor threshold (RMT); Pulse number: 2000 pulses/session (20 trains of 100 pulses, 30-second inter-train interval); EEG triggering: Stimulation pulses synchronized to the peak of the participant's ongoing θ-wave (4-7 Hz) activity. Duration: 20 sessions over 4 weeks.

BEHAVIORAL

Group Therapy

Semi-closed group therapy; 10 participants/group, 2 sessions/week, 90 minutes/session for 4 weeks (total 8 sessions). Content included: Sessions 1-2: Emotional recognition and expression training; Sessions 3-4: Cognitive restructuring; Sessions 5-6: Impulse control training; Sessions 7-8: Self-esteem building and future planning.

Trial Locations (1)

050000

The First Hospital of Hebei Medical University, Shijiazhuang

All Listed Sponsors
lead

The First Hospital of Hebei Medical University

OTHER

NCT07047534 - EEG-Triggered rTMS and Group Therapy for Adolescents With Depression and Self-Harm | Biotech Hunter | Biotech Hunter