Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis

NARecruitingINTERVENTIONAL
Enrollment

182

Participants

Timeline

Start Date

February 14, 2025

Primary Completion Date

August 30, 2025

Study Completion Date

September 1, 2025

Conditions
Peri-implant Mucositis
Interventions
PROCEDURE

Adjunctive use of Xanthan-Chlorexidine based gel

"The chlorhexidine and xanthan-based gel contains 0.5% chlorhexidine digluconate, 1% chlorhexidine dihydrochloride, and 0.5% xanthan gel. Xanthan is a polymer that creates a three-dimensional, pseudo-plastic network with water, forming a stable gel that allows a slow and prolonged release of chlorhexidine, allowing effectiveness for about 30 days. Chlorhexidine digluconate is released immediately upon application, whereas Chlorhexidine dihydrochloride is gradually delivered the following days, providing bacteriostatic and bactericidal effects for up to two weeks, helping the prevention of recolonization of treated site.~The clinician cleaned and dried the implant site using compressed air and applied the XanCHX gel on the implant sites assigned to the test group, positioning the blunt needle at the bottom of the pocket and gently extruding the product while moving it out of the site. Finally, the patient was instructed not to drink or rinse for the following hour."

Trial Locations (1)

10126

RECRUITING

AOU Città della Salute e della Scienza, Torino

All Listed Sponsors
lead

University of Turin, Italy

OTHER