Substrate Remodelling and Targeted Ablation in AF

NANot yet recruitingINTERVENTIONAL

Enrollment

160

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

November 18, 2025

Study Completion Date

August 18, 2030

Conditions

Atrial Fibrillation (AF)Atrial Fibrillation MechanismsCatheter AblationLow Voltage Areas

Interventions

PROCEDURE

Pulmonary vein reisolation

The pulmonary veins will be checked electrically and further ablation will be undertaken if they are not isolated.

PROCEDURE

Ganglionic plexi ablation

Sites where ganglionix plexi have been found will be ablated.

PROCEDURE

Substrate ablation

Areas of rate dependent conduction velocity slowing will be targeted using cathether ablation

All Listed Sponsors

lead

Barts & The London NHS Trust

OTHER

NCT07047235 - Substrate Remodelling and Targeted Ablation in AF | Biotech Hunter | Biotech Hunter