NCT07046429 - Affect of Melatonin on Sleep and Cognition in Cirrhosis | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 5, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions

Hepatic EncephalopathyCovert Hepatic EncephalopathyCirrhosisSleep Disturbances and Insomnia

Interventions

DIETARY_SUPPLEMENT

Melatonin tablet 3 mg once daily

Participants will be instructed to take 3 mg regular acting (not orally dissolving) melatonin 30 minutes before their anticipated bedtime, nightly for the 30 days preceding analysis of study endpoints.

DIETARY_SUPPLEMENT

Thiamine

Participants will be instructed to take 100 mg regular acting (not orally dissolving) thiamine 30 minutes before their anticipated bedtime, nightly for the 30 days preceding analysis of study endpoints.

Trial Locations (1)

10021

RECRUITING

NewYork-Presbyterian/Weill Cornell Medical Center, New York

All Listed Sponsors

collaborator

American Association for the Study of Liver Diseases

OTHER

lead

Weill Medical College of Cornell University

OTHER