5
Participants
Start Date
June 5, 2025
Primary Completion Date
June 5, 2026
Study Completion Date
June 5, 2026
- Group A: Platelet-rich fibrin membrane prepared intraoperatively and applied over neourethra
In this arm, a platelet-rich fibrin membrane will be prepared intraoperatively from the patient's blood using centrifugation. The prepared PRF membrane will then be applied directly over the neourethra following urethroplasty to promote healing and tissue regeneration.
Group B: Ventral dartos flap rotated over neourethra
Participants in this arm will undergo hypospadias repair with the application of a ventral dartos fascia flap. The procedure involves elevating a vascularized flap of ventral dartos fascia from the penile shaft, rotating it over the neourethra to provide additional tissue coverage and promote healing. This flap helps in reducing the risk of fistula formation and enhances vascular support to the neourethra. The surgical steps include dissecting the dartos fascia carefully, rotating it over the neourethral reconstruction, and securing it in place, followed by standard postoperative care and follow-up.
National Children's Medical Center, Tashkent
Dr Cipto Mangunkusumo General Hospital
OTHER
National Children's Medical Center, Uzbekistan
OTHER