Clinical Study to Evaluate Efficacy of Cabergoline to Coasting in Reducing the Incidence of Ovarian Hyperstimulation Syndrome

PHASE2RecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

June 30, 2025

Primary Completion Date

October 20, 2025

Study Completion Date

November 20, 2025

Conditions
Gynecologic Disease
Interventions
PROCEDURE

Coasting

In their ICSI cycle patients will continue their agonist treatment while stopping the human menopausal gonadotropin (hMG) injections for 1 to 3 days until drop of estradiol to a safe level to prevent OHSS. Early OHSS is assessed at day of embryo transfer and 7 days after this date. Late OHSS is assessed 14 days after embryo transfer.

DRUG

Cabergoline

Cabergoline is used to treat different types of medical problems that occur when too much of the hormone prolactin is produced. It can be used to treat certain menstrual problems, fertility problems in men and women, and pituitary prolactinomas

Trial Locations (1)

34518

RECRUITING

Mostafa Bahaa, Damietta

All Listed Sponsors
lead

Tanta University

OTHER