Evaluation of the Performance of Glomerular Filtration Rate Measurement Using CT Urography in Patients With a GFR Below 60 mL/Min/1.73 m²

NANot yet recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

July 15, 2025

Primary Completion Date

July 14, 2027

Study Completion Date

July 15, 2027

Conditions
Kidney DiseasesTomographyX-Ray Computed
Interventions
OTHER

Glomerular Filtration Rate measurement with iohexol clearance

After performing a 4-phase CT urography (or 3-phase CT scan, with the addition of a 4th phase for research purposes), performed for clinical indications as part of the patient's care, and using iohexol as a contrast agent, patients will undergo a biological measurement of iohexol clearance, based on serum and urine samples taken over 4 periods of 1 hour, between 3 and 7 hours after the CT scan. No iohexol will be reinjected to measure GFR. The CT scan images will be segmented by the investigator to determine the CT-measured GFR.

Trial Locations (1)

94000

Assistance Publique Hôpitaux de Paris - CHU Henri Mondor - Créteil, Créteil

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER