248
Participants
Start Date
August 1, 2025
Primary Completion Date
August 1, 2027
Study Completion Date
August 1, 2027
Nighttime Splinting
Nighttime splinting for 6 weeks.
Corticosteroid Injection
Local corticosteroid injection (triamcinolone acetonide 40mg). A single injection of triamcinolone acetonide 40mg mixed with an equal volume of 1% lidocaine is administered. The injection is performed under ultrasound guidance and anatomical landmarks to target the proximal carpal tunnel. With the wrist extended, the needle is typically inserted on the ulnar side of the palmaris longus tendon, approximately 1 cm proximal to the wrist crease. If blood is aspirated or the patient reports paresthesia (which usually indicates nerve irritation), the injection site should be adjusted.
Evaluation and Dynamic Adjustment
6 weeks later, all patients will undergo evaluation of their initial treatment. Further therapeutic decisions will be made based on physician assessment, including: continuing nighttime splinting, administering corticosteroid injections to patients who initially received only the splint, adding nighttime splinting for patients initially received only corticosteroid injections, and transitioning from nighttime splint use to continuous wear. Subsequently, evaluations will be conducted every 6 weeks, with dynamic adjustments to the treatment plan. Throughout the study period, physicians will perform electrophysiological examinations according to changes in patients' clinical status.
Jinjiang Municipal Hospital(Shanghai Sixth People's Hospital Fujian Campus), Jinjiang
Yancheng Third People's Hospital, Yancheng
Shanghai Sixth People's Hospital, Shanghai
Shanghai 6th People's Hospital
OTHER
Yun Qian
OTHER