NCT07040839View on ClinicalTrials.gov

Comparison of Omeprazole vs Vonoprazon in Treatment of H Pylori Infection

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

128

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

February 28, 2026

Study Completion Date

February 28, 2026

Conditions
H Pylori
Interventions
DRUG

Clarithromycin 500 mg

Clarithromycin 500 mg orally twice daily for 14 days

DRUG

Amoxicillin 1 g

Omeprazole 40 mg orally twice daily for 14 days, then 40 mg once daily for 4 weeks

DRUG

Omeprazole 40 mg

Omeprazole 40 mg orally twice daily for 14 days, then 40 mg once daily for 4 weeks

DRUG

Clarithromycin 500 mg

Clarithromycin 500 mg orally twice daily for 14 days

DRUG

Amoxicillin 1 g

Amoxicillin 1 g orally twice daily for 14 days

DRUG

Vonoprazan 20 mg

Vonoprazan 20 mg orally twice daily for 14 days, then 20 mg once daily for 4 weeks

DRUG

Levofloxacin 500 mg

Levofloxacin 500 mg orally once daily for 14 days

DRUG

Amoxicillin 1 g

Amoxicillin 1 g orally twice daily for 14 days

DRUG

Omeprazole 40 mg

Omeprazole 40 mg orally twice daily for 14 days, then 40 mg once daily for 4 weeks

DRUG

Levofloxacin 500 mg

Levofloxacin 500 mg orally once daily for 14 days

DRUG

Amoxicillin 1 g

Amoxicillin 1 g orally twice daily for 14 days

DRUG

Vonoprazan 20 mg

Vonoprazan 20 mg orally twice daily for 14 days, then 20 mg once daily for 4 weeks

Trial Locations (1)

092

Rehman Medical Institue, Peshawar

All Listed Sponsors
lead

Rehman Medical Institute - RMI

OTHER