Comparison of Two-Position and Four-Position Cervical Injection Techniques for Sentinel Lymph Node Mapping in Endometrial Cancer Using Methylene Blue

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

May 1, 2025

Primary Completion Date

May 1, 2026

Study Completion Date

November 1, 2026

Conditions
Endometrial NeoplasmsEndometrial Cancer Stage ISentinel Lymph NodeMetastasis
Interventions
PROCEDURE

Sentinel Lymph Node Detection/Cervical Methylene Blue Injection

Sentinel Lymph Node (SLN) detection using cervical methylene blue injection is a surgical technique designed to identify the primary lymph nodes responsible for draining the uterus in patients with endometrial cancer. The procedure involves injecting methylene blue dye into specific locations within the cervical stroma to enable lymphatic uptake. The dye subsequently travels through the lymphatic channels, allowing for intraoperative visual identification of the sentinel nodes. This targeted approach facilitates selective SLN excision for pathological evaluation, providing critical information about lymphatic involvement while minimizing the extent of surgical dissection. The effectiveness of SLN mapping is contingent upon the accuracy of the injection technique and the anatomical distribution of lymphatic drainage.

Trial Locations (2)

06230

RECRUITING

Ankara University, Ankara

Unknown

RECRUITING

Dokuz Eylul University, Izmir

All Listed Sponsors
lead

Dokuz Eylul University

OTHER