NCT07040280View on ClinicalTrials.gov

Testing the Effect of Sulforaphane, a Compound Naturally Found in Cruciferous Vegetables, on Preventing Melanoma in Patients With a Prior History of Melanoma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

February 1, 2029

Study Completion Date

August 1, 2029

Conditions
Melanoma
Interventions
DRUG

Sulforaphane (broccoli sprout extract)

Sulforaphane - Three tablets of Avmacol® Extra Strength \[Nutramax\] by mouth, once daily, for 12 months.

DRUG

Placebo

Three tablets by mouth, once daily, for 12 months

DEVICE

Derma-AI

Photographs of lesions as part of the clinical exam at baseline, three (3) months, and twelve (12) months. These photographs will be submitted for assessment by a software called Derma-AI, which tracks moles over time for changes in size, number, and appearance

Trial Locations (1)

15213

UPMC Hillman Cancer Center, Pittsburgh

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

lead

Eastern Cooperative Oncology Group

NETWORK

NCT07040280 - Testing the Effect of Sulforaphane, a Compound Naturally Found in Cruciferous Vegetables, on Preventing Melanoma in Patients With a Prior History of Melanoma | Biotech Hunter | Biotech Hunter