Study of Cardiac Power Index During Supine, Lateral, and Between Left and Right Positions During Two- and One-Lung Ventilation (OLV): Comparison of Hemodynamic Changes After Lung Recruitment Maneuver and Fluid Challenge Among Responders and Non-Responders (SVI, MAP, CPI Changes).

NAActive, not recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

May 6, 2025

Primary Completion Date

May 6, 2026

Study Completion Date

May 6, 2027

Conditions
Thoracic Surgical ProceduresOne-lung Ventilation (OLV)Hemodynamic Changes
Interventions
OTHER

Fluid challenge during one-lung ventilation (OLV) in the lateral decubitus position

During OLV, a lung recruitment maneuver will be performed, followed by measurements of CPI, CI, SVI, and MAP. A fluid challenge using 250 mL of normal saline (0.9% NaCl) will be administered. Hemodynamic parameters will be recorded at 2 and 5 minutes post-infusion. Patients will be classified as responders (SVI and MAP increase ≥10%) or non-responders. Changes in CPI will also be recorded accordingly.

DEVICE

Hemodynamic monitoring

Invasive hemodynamic monitoring will be performed using the HemoSphere device (Edwards Lifesciences).

Trial Locations (1)

12462

Attikon Hospital, Athens

All Listed Sponsors
lead

Maria Fountoulaki

OTHER

NCT07037225 - Study of Cardiac Power Index During Supine, Lateral, and Between Left and Right Positions During Two- and One-Lung Ventilation (OLV): Comparison of Hemodynamic Changes After Lung Recruitment Maneuver and Fluid Challenge Among Responders and Non-Responders (SVI, MAP, CPI Changes). | Biotech Hunter | Biotech Hunter