120
Participants
Start Date
January 18, 2025
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2029
bariatric surgery
This is a prospective observational study evaluating the metabolic and tissue-level effects of bariatric surgery in obese individuals. The intervention includes either laparoscopic sleeve gastrectomy (LSG) or Roux-en-Y gastric bypass (RYGB), performed according to standard clinical guidelines. No experimental procedures are added beyond routine care. Skeletal muscle quality and visceral fat distribution are assessed using MRI and clinical biomarkers at multiple postoperative time points (baseline, 3 months, 12 months, and annually up to 5 years). A healthy control group undergoes baseline evaluation only, without surgical intervention.
Xiangya Third Hospital, Central South University, Changsha
Shaihong Zhu
OTHER