Changes in Fat and Muscle Tissue Function and Their Impact on Metabolic Health After Bariatric Surgery

Active, not recruitingOBSERVATIONAL
Enrollment

120

Participants

Timeline

Start Date

January 18, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2029

Conditions
Obesity and Obesity-related Medical ConditionsSarcopenic ObesityAdipose Tissue, Abdominal
Interventions
PROCEDURE

bariatric surgery

This is a prospective observational study evaluating the metabolic and tissue-level effects of bariatric surgery in obese individuals. The intervention includes either laparoscopic sleeve gastrectomy (LSG) or Roux-en-Y gastric bypass (RYGB), performed according to standard clinical guidelines. No experimental procedures are added beyond routine care. Skeletal muscle quality and visceral fat distribution are assessed using MRI and clinical biomarkers at multiple postoperative time points (baseline, 3 months, 12 months, and annually up to 5 years). A healthy control group undergoes baseline evaluation only, without surgical intervention.

Trial Locations (1)

410013

Xiangya Third Hospital, Central South University, Changsha

All Listed Sponsors
lead

Shaihong Zhu

OTHER

NCT07035483 - Changes in Fat and Muscle Tissue Function and Their Impact on Metabolic Health After Bariatric Surgery | Biotech Hunter | Biotech Hunter