NCT07034560View on ClinicalTrials.gov

Effectiveness of Oral Melatonin vs Oral Tranexamic Acid in the Treatment and Recurrence of Melasma

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

November 12, 2024

Primary Completion Date

November 6, 2025

Study Completion Date

November 6, 2025

Conditions
MelasmaTreatment OutcomeRecurrence
Interventions
DRUG

Tranexamic Acid (TXA)

500 mg oral tranexamic acid (Transamin®), taken once daily at bedtime for 12 weeks.

DRUG

melatonin (Circadin)

2 mg oral melatonin (Circadin®), taken once daily at bedtime for 12 weeks.

DRUG

Placebo

Placebo capsule identical in appearance, taken once daily at bedtime for 12 weeks.

Trial Locations (1)

10330

Benchakitti Park Hospital, Bangkok

All Listed Sponsors
lead

Thammasat University

OTHER

NCT07034560 - Effectiveness of Oral Melatonin vs Oral Tranexamic Acid in the Treatment and Recurrence of Melasma | Biotech Hunter | Biotech Hunter