Evaluation of Electrical and Hemodynamic Effects of Different Pacing Strategies in CRT Candidates

NACompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

June 3, 2024

Primary Completion Date

May 20, 2025

Study Completion Date

May 20, 2025

Conditions
Heart FailureCRT and/or ICD
Interventions
PROCEDURE

Sequential ventricular pacing at five sites

"This intervention involves sequential temporary pacing at five distinct ventricular sites within the same patient during a single electrophysiological study. The pacing sites include:His bundle pacing (HBP),Deep septal pacing (DSP),Left ventricular septal pacing (LVSP),Non-selective left bundle branch pacing (NS-LBBP),Selective left bundle branch pacing (SLBBP).~Each pacing modality is tested under identical hemodynamic and electrophysiological conditions using a fixed output and AV delay. Electrical parameters and acute hemodynamic responses are recorded for each site. The study uses a within-subject crossover design, allowing direct intra-individual comparison of different pacing strategies in patients meeting standard CRT indications. No long-term device implantation is involved during this phase of the study."

Trial Locations (1)

Unknown

Zhongshan Hospital, Fudan University, Shanghai

All Listed Sponsors
lead

Shanghai Zhongshan Hospital

OTHER

NCT07032064 - Evaluation of Electrical and Hemodynamic Effects of Different Pacing Strategies in CRT Candidates | Biotech Hunter | Biotech Hunter