Effectiveness of an AI-Enabled Stratified Management System for Premature Coronary Artery Disease

NARecruitingINTERVENTIONAL
Enrollment

4,900

Participants

Timeline

Start Date

August 8, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

July 31, 2027

Conditions
Premature Coronary Heart Disease
Interventions
COMBINATION_PRODUCT

AI-Enabled Stratified Management System

After discharge, participants install SMART-CHD, sync their EHR data, and complete a 10-minute orientation. They then use the app's OCR-assisted surveys to report lifestyle, lab, and event data, while paired wearables stream continuous vitals. AI voice calls and a CRC-managed WeChat group deliver reminders and support. The app's embedded predictive models stratify them into risk tiers and generate tier-specific follow-up schedules. Personalized lifestyle modification guidance, dietary plans, and medication adjustment recommendations are generated by the platform's module. Automated alerts and teleconsultation options are triggered upon detection of high-risk signs or abnormal results, ensuring timely clinical intervention and enhanced secondary prevention.

COMBINATION_PRODUCT

Usual Post-Discharge Care

Usual discharge protocol comprising verbal and printed discharge instructions addressing medication schedules, follow-up timelines, and lifestyle optimization strategies.

Trial Locations (16)

100037

RECRUITING

Fuwai Hospital, Chinese Academy of Medical Sciences/National Center for Cardiovascular Diseases, Beijing

210029

NOT_YET_RECRUITING

The First Affiliated Hospital of Nanjing Medical University, Nanjing

225001

NOT_YET_RECRUITING

Northern Jiangsu People's Hospital, Yangzhou

230001

NOT_YET_RECRUITING

The First Affiliated Hospital of University of Science and Technology of China, Hefei

310009

NOT_YET_RECRUITING

The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou

400042

NOT_YET_RECRUITING

The Affiliated Hospital of Southwest Medical University, Luzhou

450000

NOT_YET_RECRUITING

Henan Provincial Chest Hospital, Zhengzhou

NOT_YET_RECRUITING

Zhengzhou University Affiliated Zhengzhou Central Hospital, Zhengzhou

NOT_YET_RECRUITING

Zhengzhou University Fuwai Central China Cardiovascular Hospital, Zhengzhou

471003

NOT_YET_RECRUITING

The First Affiliated Hospital of Henan University of Science and Technology, Luoyang

518057

NOT_YET_RECRUITING

Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, Shenzhen

710004

NOT_YET_RECRUITING

The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an

710061

NOT_YET_RECRUITING

The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an

050000

NOT_YET_RECRUITING

The First Hospital of Hebei Medical University, Shijiazhuang

NOT_YET_RECRUITING

The Second Hospital Of Hebe Medical University, Shijiazhuang

030024

NOT_YET_RECRUITING

Shanxi Cardiovascular Disease Hospital, Taiyuan

All Listed Sponsors
lead

China National Center for Cardiovascular Diseases

OTHER_GOV

NCT07031531 - Effectiveness of an AI-Enabled Stratified Management System for Premature Coronary Artery Disease | Biotech Hunter | Biotech Hunter