Assessment of Er:YAG Laser-Assisted Surgical Treatment in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Clinical Trial

NACompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

February 1, 2021

Primary Completion Date

August 1, 2023

Study Completion Date

May 1, 2025

Conditions
Medication-Related Osteonecrosis of Jaw
Interventions
PROCEDURE

irradiation with Er:YAG laser

An Er:YAG laser (LightTouch, LightInstruments, Yokneam, Israel) was used with the following parameters: 400mJ (millijoules), 6W (Watt), 15Hz (Hertz), 5/8 water cooling, laser tip with a diameter of 800 microns. Tissue debridement continued until hard, healthy, lively bleeding bone was exposed, indicative of normal bone.

PROCEDURE

Tissue preparation

Rose-shaped rotary drills (8 mm diameter) were used with water cooling at a speed not exceeding 40.000 rpm. Tissue preparation limits were consistent with those used for the Er:YAG laser group.

Trial Locations (1)

Unknown

Wroclaw Medical University, Wroclaw

All Listed Sponsors
lead

Wroclaw Medical University

OTHER

NCT07029815 - Assessment of Er:YAG Laser-Assisted Surgical Treatment in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Clinical Trial | Biotech Hunter | Biotech Hunter