40
Participants
Start Date
July 1, 2025
Primary Completion Date
January 15, 2026
Study Completion Date
January 30, 2026
Limosilactobacillus reuteri Prodentis®
Daily administration of Limosilactobacillus reuteri Prodentis® (1 oral tablet per day, taken after brushing in the evening), as an adjunct to non-surgical periodontal therapy and standard home care. Administered for 6 months only in the experimental arm.
Coenzyme Q10 Toothpaste
Twice-daily use of a commercially available toothpaste containing coenzyme Q10, used as part of a home oral hygiene regimen for 6 months. All participants in both study arms will use the same toothpaste, with or without adjunctive probiotic supplementation.
RECRUITING
Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia, Pavia
University of Pavia
OTHER