340
Participants
Start Date
June 10, 2025
Primary Completion Date
June 1, 2026
Study Completion Date
May 31, 2027
Expandable OLIF cage with posterior bone grafting
This intervention involves the use of a novel expandable OLIF cage that allows intraoperative height adjustment and posterior bone grafting through a dedicated channel. The device is designed to restore intervertebral height and lumbar lordosis while minimizing endplate injury. Bone grafts (autologous or synthetic) are delivered after expansion to enhance fusion. This design aims to reduce cage subsidence, improve fusion rates, and simplify the surgical workflow compared to conventional OLIF cages with fixed heights.
Conventional OLIF cage
Participants in the control group will undergo oblique lateral interbody fusion (OLIF) using a standard non-expandable interbody fusion cage. The cage has a fixed height and is inserted via the retroperitoneal approach. Bone grafts are packed into the cage prior to insertion through the anterior or lateral window. This represents the current standard practice for OLIF procedures and does not allow intraoperative height adjustment or posterior graft delivery. The procedure follows conventional OLIF surgical protocols without additional design modifications.
The First Affiliated Hospital of Zhengzhou University
OTHER
Peking University People's Hospital
OTHER
Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine
UNKNOWN
Jinan Hospital, Xuanwu Hospital, Capital Medical University
UNKNOWN
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
OTHER
Shanghai changzheng hospital, Naval Medical University
UNKNOWN
The Affiliated Hospital of Qingdao University
OTHER