Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)

PHASE1RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 28, 2025

Primary Completion Date

February 22, 2028

Study Completion Date

February 22, 2029

Conditions
Alcohol Use Disorder
Interventions
DRUG

Intravenous Ethanol

Intravenous ethanol infusion before PET Scan

DRUG

18F-PF-06445974

Injected IV followed by PET scanning

Trial Locations (1)

20892

RECRUITING

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute of Mental Health (NIMH)

NIH

NCT07027839 - Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B) | Biotech Hunter | Biotech Hunter