Oliceridine on Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery

PHASE4RecruitingINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

July 21, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

January 31, 2026

Conditions
Gynecologic Surgical ProceduresPostoperative Nausea and Vomiting (PONV)Laparoscopy
Interventions
DRUG

Oliceridine

For gynecological laparoscopic surgery, general anesthesia was induced with Oliceridine at a dose of 0.06 mg/kg (Yichang Renfu Pharmaceutical Co., Ltd., China). Intraoperative analgesia was administered with a total dose of Oliceridine ranging from 0.1 to 0.15 mg/kg. Postoperatively, Oliceridine was administered through a patient-controlled analgesia (PCA) system.

DRUG

Sufentanil

For gynecological laparoscopic surgery, general anesthesia was induced with Sufentanil at a dose of 0.3 µg/kg (Yichang Renfu Pharmaceutical Co., Ltd., China). Intraoperative analgesia was provided with a total dose of Oliceridine ranging from 0.5 to 0.8 µg/kg. Postoperatively, Sufentanil was administered through a patient-controlled analgesia (PCA) system.

Trial Locations (1)

410011

RECRUITING

The Second Xiangya Hospital of Central South University, Changsha

All Listed Sponsors
lead

YanYing Xiao

OTHER