Personalized Accelerated Intermittent Theta Burst Stimulation for Post-Acute Suicidal Ideation

NANot yet recruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

April 30, 2027

Study Completion Date

May 31, 2027

Conditions
Major Depressive Disorder (MDD)Suicidal Ideation
Interventions
DEVICE

TMS

"The protocol involves delivering sessions of intermittent theta burst stimulation (iTBS) of 60 cycles of 10 bursts of three pulses at 50 Hz were delivered in 2-second trains (5 Hz) with an 8-second intertrain interval. Stimulation sessions will be delivered hourly. Ten sessions will be applied per day (18,000 pulses/day) for 5 consecutive days (90,000 pulses in total). Stimulation will be delivered at 90% resting motor threshold (rMT) adjusted for cortical depth.~MR brain imaging will be used with the Localite Neuronavigation System (Localite GmbH, Sankt Augustin, Germany) to position the TMS coil over the individualized stimulation target."

All Listed Sponsors
lead

University of California, Davis

OTHER