Complex Arrhythmia Registry

Not yet recruitingOBSERVATIONAL
Enrollment

4,000

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

December 31, 2031

Study Completion Date

December 31, 2031

Conditions
Atrial Fibrillation (AF)Ventricular Tachycardia (VT)
Interventions
PROCEDURE

AF ablation

Catheter ablation will be performed under general anesthesia or local anesthesia. Pulmonary vein isolation (PVI) was performed in all patients. Beyond this mandatory step, the specific ablation strategy/protocol and ablation parameters/settings will be determined at the discretion of the operating physicians at each participating center.

PROCEDURE

VT ablation

For patients with hemodynamically stable VT, comprehensive chamber mapping (including activation mapping, substrate mapping, and entrainment mapping) is recommended. This aims to elucidate the VT activation sequence and identify the critical isthmus. Precise ablation targeting the isthmus should be performed to terminate the VT. For patients with hemodynamically unstable VT, substrate mapping during sinus rhythm can be performed first. This includes identification of low-voltage zones and abnormal electrograms (e.g., late potentials, local abnormal ventricular activities - LAVAs). Targeted substrate modification ablation should then be conducted based on the mapping findings. For all patients, complete substrate mapping is recommended after VT termination.

Trial Locations (1)

Unknown

Beijing Anzhen Hospital, Capital Medical University, Beijing

All Listed Sponsors
lead

Beijing Anzhen Hospital

OTHER