Effect of Arginine and Glutamine Oral Suspension on EGF in Radiation Induced Oral Mucositis: A Trible Blinded Randomized Controlled Clinical Trial

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

69

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

June 15, 2025

Study Completion Date

July 1, 2025

Conditions
Radiation Induced Oral MucositisOral MucositisOral Mucositis Due to Radiation
Interventions
DIETARY_SUPPLEMENT

L-arginine Oral Suspension

"Type: Dietary supplement~Dosage: 5 g L-arginine + 5 g maltodextrin~Route: Oral (swish-and-swallow)~Frequency: Three times daily, 30 minutes before meals~Duration: From the 2nd to the 7th week of radiotherapy"

DIETARY_SUPPLEMENT

L-glutamine Oral Suspension

"Type: Dietary supplement~Dosage: 5 g L-glutamine + 5 g maltodextrin~Route: Oral (swish-and-swallow)~Frequency: Three times daily, 30 minutes before meals~Duration: From the 2nd to the 7th week of radiotherapy"

DIETARY_SUPPLEMENT

Maltodextrin Oral Suspension (Control)

"Type: Placebo comparator~Dosage: 10 g maltodextrin~Route: Oral (swish-and-swallow)~Frequency: Three times daily, 30 minutes before meals~Duration: From the 2nd to the 7th week of radiotherapy"

Trial Locations (1)

10226

Faculty of Dentistry, Future University in Egypt, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER