Is the Combine Prolotherapy More Effective Than the Traditional Prolotherapy in Patients With Temporomandibular Joint Hypermobility?

PHASE4CompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

January 1, 2019

Primary Completion Date

January 1, 2022

Study Completion Date

January 1, 2025

Conditions
Temporomandibular Disorders (TMD)Temporomandibular PainHypermobility Syndrome (Disorder)Hypermobility, JointArthrocentesisProlotherapy
Interventions
DRUG

prolotherapy solution of 20% dextrose

Polotherapy, it involves injecting an irritant solution into weakened joints, ligaments, or tendons to stimulate collagen production and tissue repair at fibro-osseous junctions.

DRUG

Arthrocentesis with ringer solution

Integrating arthrocentesis with prolotherapy may enhance therapeutic outcomes by addressing both the mechanical and inflammatory aspects of TMJ hypermobility. This dual-modality technique presents a promising minimally invasive option for clinicians managing patients with joint instability.

Trial Locations (1)

61040

Karadeniz Technical University, Trabzon

All Listed Sponsors
lead

Karadeniz Technical University

OTHER

NCT07020455 - Is the Combine Prolotherapy More Effective Than the Traditional Prolotherapy in Patients With Temporomandibular Joint Hypermobility? | Biotech Hunter | Biotech Hunter