Safety of Etomidate-propofol Mixture vs. Propofol for Total Intravenous Anesthesia in Elderly Patients Undergoing Abdominal Surgery

NARecruitingINTERVENTIONAL
Enrollment

166

Participants

Timeline

Start Date

February 1, 2025

Primary Completion Date

May 30, 2026

Study Completion Date

June 5, 2026

Conditions
Etomidate Combined With PropofolHypertension
Interventions
DRUG

EP mixture

Patients will receive etomidate - propofol mixture during induction and maintenance. Sufentanil 0.2-0.7 μg/kg,Cisatracurium 0.15 mg/kg,EP mixture(E:P=1:2) 0.1-0.25 ml/kg for induction, EP mixture 0.4\~ 1.2 ml/kg/h and remifentanil 0.05μg/kg/min \~0.3 μg/kg/min for maintenance.

DRUG

Propofol

Patients will receive propofol during induction and maintenance.Sufentanil 0.2-0.7 μg/kg,Cisatracurium 0.15 mg/kg,propofol 0.1-0.25 ml/kg for induction, propofol 0.4\~ 1.2 ml/kg/h and remifentanil 0.05μg/kg/min \~0.3 μg/kg/min for maintenance.

Trial Locations (1)

430030

RECRUITING

Tongji hospital, Wuhan

All Listed Sponsors
lead

Tongji Hospital

OTHER