Trial to Assess the Efficacy and Safety During Convective Radiofrequency Water Vapor Thermal Therapy (REZUM) for Benign Prostate Hyperplasia

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

August 31, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
Benign Prostate Hypertrophy(BPH)
Interventions
DRUG

Methoxyflurane - Penthrox

Penthrox is a brand name for a drug called methoxyflurane. It is an inhaled analgesic (pain-relieving) agent used primarily for the relief of moderate to severe pain, typically in emergency medical situations or during minor medical procedures. Penthrox is administered by inhaling the vapors through a hand-held inhaler device. It acts quickly to provide pain relief and has a relatively short duration of action.

OTHER

Control

This intervention will be the control group only, receiving deep IV sedation.

DRUG

Percocet Pill

Percocet will be given in conjunction with methoxyfluorane and lorazepam

DRUG

Lorazepam (drug)

Lorazepam will be given in conjunction with penthrox and percocet.

Trial Locations (1)

R3K 1M3

Men's Health Clinic Manitoba, Winnipeg

All Listed Sponsors
lead

University of Manitoba

OTHER