Low-Flow Desflurane vs Sevoflurane: Impact on Physiology and Recoveryand Recovery Profiles in Adult ENT Surgery

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 10, 2025

Primary Completion Date

September 10, 2025

Study Completion Date

September 20, 2025

Conditions
Anesthesia, General
Interventions
DRUG

Sevoflurane

Sevoflurane will be administered via inhalation under low-flow anesthesia conditions. The concentration will be maintained at 2-3% (0.8-1 MAC) with a fresh gas flow of 1 L/min (50% oxygen and 50% air) after induction. Used in Group S (Sevoflurane Low-Flow Anesthesia Arm).

DRUG

Desflurane

Desflurane will be administered via inhalation under low-flow anesthesia conditions. The concentration will be maintained at 4-6% (0.8-1 MAC) with a fresh gas flow of 1 L/min (50% oxygen and 50% air) after induction. Used in Group D (Desflurane Low-Flow Anesthesia Arm).

Trial Locations (1)

63100

RECRUITING

Veli Fahri Pehlivan, Sanliurfa

All Listed Sponsors
lead

Harran University

OTHER

NCT07016308 - Low-Flow Desflurane vs Sevoflurane: Impact on Physiology and Recoveryand Recovery Profiles in Adult ENT Surgery | Biotech Hunter | Biotech Hunter