Botulinum Toxin Injection After Sternotomies to Improve Scar Aspect and Impact

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

July 5, 2025

Primary Completion Date

February 28, 2027

Study Completion Date

February 28, 2027

Conditions
Sternotomy Closure,Open Heart Surgery
Interventions
DRUG

Botulinum toxin injection

"Intervention will be made immediately after surgery, still under general anesthesia, by the cardiac surgeon, after suture.~Each patient will receive (either in the lower part or the upper part of the scar according to randomization) 50 international units (IU) of type A botulinum toxin (Botox®, Allergan aesthetics) diluted in 1 mL of saline to enable injection of 5 IU at each point, every centimeter, at 1 cm of each scar side.~An equivalent volume of saline will be injected under the same modalities in the other part of the scar."

Trial Locations (1)

33000

Centre Hospitalier Universitaire de Bordeaux, Bordeaux

All Listed Sponsors
lead

University Hospital, Bordeaux

OTHER