Pulsed Field Ablation for Cavotricuspid Isthmus Dependent Atrial Flutter Cohort Study

NANot yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 30, 2025

Primary Completion Date

March 31, 2026

Study Completion Date

June 30, 2026

Conditions
Cavotricuspid Isthmus Dependent Atrial Flutter
Interventions
DEVICE

CTI ablation

CTI ablation will be performed with PFA. Before ablation, The RA geometry will be created with a multipolar catheter. Coronary angiogram will be performed at baseline in LAO 45 degree before and after each set of ablations. After ablation, a 15-minute waiting period will be mandated. The CTI block will be rechecked with 3D mapping system and multipolar catheter. If there is persistent CTI conduction, ablation will be repeated until CTI block is achieved. This will be followed by another 15 minutes of waiting period before rechecking the block across CTI, and so on. TNG will be prepared. It will be given via intracoronary route in 100-200mcg bolus if severe spasm is observed. If CTI block cannot be achieved with repeated PFA ablation, ablation with radiofrequency will be allowed to achieve block. Patient will come back for follow up at 3 months for a remapping procedure. During the remapping procedure, a RCA coronary angiogram will be performed to exclude late coronary damage.

Trial Locations (1)

Unknown

Prince of Wales Hospital, Hong Kong

All Listed Sponsors
lead

Chinese University of Hong Kong

OTHER

NCT07012460 - Pulsed Field Ablation for Cavotricuspid Isthmus Dependent Atrial Flutter Cohort Study | Biotech Hunter | Biotech Hunter