Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression(SMART-I)

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

June 20, 2025

Primary Completion Date

June 30, 2027

Study Completion Date

December 31, 2027

Conditions
Major Depressive Disorder (MDD)
Interventions
DRUG

Sertraline

Commonly used oral antipsychotics intervention therapy.

DRUG

Agomelatine

Commonly used oral antipsychotics intervention therapy.

DRUG

Aripiprazole

Commonly used oral antipsychotics intervention therapy.

Trial Locations (1)

400016

The First Affiliated Hospital of Chongqing Medical University, Chongqing

All Listed Sponsors
lead

Xinyu Zhou

OTHER